Medical NeuroScience Cluster Publications by
Scholze Petra, Assoc.Prof. Priv.Doz. Mag. Dr. :

2023 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2008 2007 2006 2005 2004 2002 2001 2000 1999 1996

2023 Original Articles

• Arias H, De Deurwaerdère P, Scholze P, Sakamoto S, Hamachi I, Di Giovanni G, Chagraoui A (2023) Coronaridine congeners induce sedative and anxiolytic-like activity in naïve and stressed/anxious mice by allosteric mechanisms involving increased GABAA receptor affinity for GABA Eur J Pharmacol, 953: 175854

2020 Original Articles

• Perniss A, Latz A, Boseva I, Papadakis T, Dames C, Meisel C, Meisel A, Scholze P, Kummer W, Krasteva-Christ G (2020) Acute nicotine administration stimulates ciliary activity via α3β4 nAChR in the mouse trachea Int. Immunopharmacol., 84: 106496
• Tsymala I, Nigritinou M, Zeka B, Schulz R, Niederschick F, Matković M, Bauer I, Szalay M, Schanda K, Lerch M, Misu T, Fujihara K, Bennett J, Dahle C, Pache F, Rommer P, Leutmezer F, Illes Z, Leite M, Palace J, Scholze P, Reindl M, Lassmann H, Bradl M (2020) Induction of aquaporin 4-reactive antibodies in Lewis rats immunized with aquaporin 4 mimotopes Acta Neuropathologica Communications, 15; 8 (1)
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• Arias H, Do Rego J, Do Rego J, Chen Z, Anouar Y, Scholze P, Gonzales E, Huang R, Chagraoui A (2020) Coronaridine congeners potentiate GABAA receptors and induce sedative activity in mice in a benzodiazepine-insensitive manner Prog Neuropsychopharmacol Biol Psychiatry, 101: 109930

2019 Original Articles

• Maleeva G, Wutz D, Rustler K, Nin‐Hill A, Alfonso‐Prieto M, Petukhova E, Bautista‐Barrufet A, Gomila‐Juaneda A, Scholze P, Peiretti F, Rovira C, König B, Gorostiza P, Bregestovski P (2019) A photoswitchable GABA receptor channel blocker Br J Pharmacol, 176(15): 2661-2677
• Simeone X, Karch R, Ciuraszkiewicz A, Orr‐Urtreger A, Lemmens‐Gruber R, Scholze P, Huck S (2019) The role of the nAChR subunit α5, β2, and β4 on synaptic transmission in the mouse superior cervical ganglion Phys Reports, 7 (6): e14023
• Dorninger F, König T, Scholze P, Berger M, Zeitler G, Wiesinger C, Gundacker A, Pollak D, Huck S, Just W, Forss-Petter S, Pifl C, Berger J (2019) Disturbed Neurotransmitter Homeostasis in Ether Lipid Deficiency Hum Mol Genet, 28(12): 2046-2061
• Prevot T, Li G, Vidojevic A, Misquitta K, Fee C, Santrac A, Knutson D, Stephen M, Kodali R, Zahn N, Arnold L, Scholze P, Fisher J, Marković B, Banasr M, Cook J, Savic M, Sibille E (2019) Novel Benzodiazepine-Like Ligands with Various Anxiolytic, Antidepressant, or Pro-Cognitive Profiles Mol Psychiatry, 5(2): 84-97

2018 Original Articles

• Ricken G, Schwaiger C, De Simoni D, Pichler V, Lang J, Glatter S, Macher S, Rommer P, Scholze P, Kubista H, Koneczny I, Höftberger R (2018) Detection Methods for Autoantibodies in Suspected Autoimmune Encephalitis Front Neurol, 9: 841
• Forget B, Scholze P, Langa F, Morel C, Pons S, Mondoloni S, Besson M, Durand-de Cuttoli R, Hay A, Tricoire L, Lambolez B, Mourot A, Faure P, Maskos U (2018) A Human Polymorphism in CHRNA5 Is Linked to Relapse to Nicotine Seeking in Transgenic Rats Curr Biol., 28 (20): 3244-3253.e7
• Siebert D, Bampali K, Puthenkalam R, Varagic Z, Sarto-Jackson I, Scholze P, Sieghart W, Mihovilovic M, Schnürch M, Ernst M (2018) Engineered Flumazenil Recognition Site Provides Mechanistic Insight Governing Benzodiazepine Modulation in GABAA Receptors ACS Chem Biol, 13: 2040-2047
• Siebert D, Wieder M, Schlener L, Scholze P, Boresch S, Langer T, Schnürch M, Mihovilovic M, Richter L, Ernst M, Ecker G (2018) SAR-Guided Scoring Function and Mutational Validation Reveal Binding Mode of CGS-8216 at the α1+/γ2- Benzodiazepine Site J Chem Inf Model., 58 (8): 1682-1696
• Elgarf A, Siebert D, Steudle F, Draxler A, Li G, Huang S, Cook J, Ernst M, Scholze P (2018) Different Benzodiazepines Bind with Distinct Binding Modes to GABAA Receptors ACS Chem Biol, 13 (8): 2033-2039
• Batinić B, Stanković T, Stephen M, Kodali R, Tiruveedhula V, Li G, Scholze P, Marković B, Obradović A, Ernst M, Cook J, Savić M (2018) Attaining in vivo selectivity of positive modulation of α3βγ2 GABA A receptors in rats: A hard task! Eur Neuropsychopharmacol, 28 (8): 903-914
• Treven M, Siebert D, Holzinger R, Bampali K, Fabjan J, Varagic Z, Wimmer L, Steudle F, Scholze P, Schnürch M, Mihovilovic M, Ernst M (2018) Towards Functional Selectivity for α6β3γ2 GABAA Receptors: A Series of Novel Pyrazoloquinolinones Br J Pharmacol, 175 (3): 419-428

2017 Original Articles

• Simeone X, Siebert D, Bampali K, Varagic Z, Treven M, Rehman S, Pyszkowski J, Holzinger R, Steudle F, Scholze P, Mihovilovic M, Schnürch M, Ernst M (2017) Molecular tools for GABAA receptors: High affinity ligands for β1-containing subtypes Sci Rep, 7 (1) : 5674

2016 Original Articles

• Stamenić T, Poe M, Rehman S, Santrač A, Divović B, Scholze P, Ernst M, Cook J, Savić M (2016) Ester to amide substitution improves selectivity, efficacy and kinetic behavior of a benzodiazepine positive modulator of GABAA receptors containing the α5 subunit Eur J Pharmacol, 791: 433-443

2015 Original Articles

• Mika J, Schwarz K, Wanzenboeck H, Scholze P, Bertagnolli E (2015) Investigation of neurotrophic factor concentrations with a novel in vitro concept for peripheral nerve regeneration J Neurosci Res, 93 (11): 1631-1640
• Xanthos D, Beiersdorf J, Thrun A, Ianosi B, Orr-Urtreger A, Huck S, Scholze P (2015) Role of α5-containing nicotinic receptors in neuropathic pain and response to nicotine Neuropharmacology, 95: 37-49
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2014 Original Articles

• Beiranvand F, Zlabinger C, Orr-Urtreger A, Ristl R, Huck S, Scholze P (2014) Nicotinic acetylcholine receptors control acetylcholine and noradrenaline release in the rodent habenulo-interpeduncular complex Br J Pharmacol, 171 (23): 5209-5224
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• Mirheydari P, Ramerstorfer J, Varagic Z, Scholze P, Wimmer L, Mihovilovic MM, Sieghart W, Ernst M (2014) Unexpected properties of delta-containing GABA-A receptors in response to ligands interacting with the alpha+beta-site Neurochem Res, 39 (6): 1057-1067

2013 Original Articles

• Ciuraszkiewicz A, Schreibmayer W, Platzer D, Orr-Urtreger A, Scholze P, Huck S. (2013) Single-channel properties of α3β4, α3β4α5, and α3β4β2 nicotinic ACh receptors in mice lacking specific nAChR subunits J Physiol, 591: 3271-3288
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2012 Original Articles

• Berger ML, Pöhler T, Schadt O, Stanger M, Rebernik P, Scholze P, Noe CR (2012) Exploring the Polyamine Regulatory Site of the NMDA Receptor: a Parallel Synthesis Approach ChemMedChem, 8 (1): 82-94
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• Scholze P, Koth G, Orr-Urtreger A, Huck S (2012) Subunit composition of α5-containing nicotinic receptors in the rodent habenula J Neurochem, 121(4): 551-560
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2011 Original Articles

• Scholze P, Ciuraszkiewicz A, Grössl F, Orr-Urtreger A, McIntosh JM, Huck S (2011) Alpha4beta2 Nicotinic Acetylcholine Receptors n the Early Postnatal Mouse Superior Cervical Ganglion Dev. Neurobiology, 71 (5): 390-399
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• Peneder TM, Scholze P, Berger ML, Reither H, Heinze G, Bertl J, Bauer J, Richfield EK, Hornykiewicz O, Pifl C (2011) Chronic exposure to manganese decreases striatal dopamine turnover in human alpha-synuclein transgenic mice Neuroscience, 180: 280-292

2010 Original Articles

• David R, Ciuraszkiewicz A, Simeone X, Orr-Urtreger A, Papke RL, McIntosh JM, Huck S, Scholze P (2010) Biochemical and functional properties of distinct nicotinic acetylcholine receptors in the superior cervical ganglion of mice with targeted deletions of nAChR subunit genes Eur J Neurosci, 6: 978-993
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2008 Original Articles

• Putz G, Kristufek D, Orr-Urtreger A, Changeux JP, Huck S, Scholze P (2008) Nicotinic acetylcholine receptor-subunit mRNAs in the mouse superior cervical ganglion are regulated by development but not by deletion of distinct subunit genes J Neurosci Res, 86: 972-981
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2007 Original Articles

• Scholze P., Orr-Urtreger A., Changeux J.-P., McIntosh J.M. , Huck S (2007) Catecholamine outflow from mouse and rat brain slice preparations evoked by nicotinic acetylcholine receptor activation and electrical field stimulation Br J Pharmacol, 151: 414-422
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2006 Original Articles

• Betz H, Gomeza J, Armsen W, Scholze P, Eulenburg V (2006) Glycine transporters: essential regulators of synaptic transmission Biochem. Soc. Trans., 34: 55-58
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2005 Original Articles

• Seidel S, Singer EA, Just H, Farhan H, Scholze P, Kudlacek O, Holy M, Koppatz K, Krivanek P, Freissmuth M, Sitte HH (2005) Amphetamines take two to tango: an oligomer-based counter-transport model of neurotransmitter transport explores the amphetamine action Mol Pharmacol, 67: 140-151
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• Hilber B, Scholze P, Dorostkar MM, Sandtner W, Holy M, Boehm S, Singer EA, Sitte HH (2005) Serotonin-transporter mediated efflux: a pharmacological analysis of amphetamines an non-amphetamines Neuropharmacology, 49: 811-819
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2004 Original Articles

• Ohno K, Koroll M, El FO, Scholze P, Gomeza J, Betz H (2004) The neuronal glycine transporter 2 interacts with the PDZ domain protein syntenin-1 Mol Cell Neurosci, 26: 518-529
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• Farhan H, Korkhov VM, Paulitschke V, Dorostkar MM, Scholze P, Kudlacek O, Freissmuth M, Sitte HH (2004) Two discontinuous segments in the carboxyl terminus are required for membrane targeting of the rat gamma-aminobutyric acid transporter-1 (GAT1) J Biol Chem, 279: 28553-28563
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2002 Original Articles

• Sitte H, Singer E, Scholze P (2002) Bi-directional transport of GABA in human embryonic kidney (HEK-293) cells stably expressing the rat GABA transporter GAT-1 Br J Pharmacol, 135 (1): 93-102
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2001 Original Articles

• Scholze P, Sitte H, Singer E (2001) Substantial loss of substrate by diffusion during uptake in HEK-293 cells expressing neurotransmitter transporters Neurosci Lett, 309 (3): 173-176
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• Schmid J, Scholze P, Kudlacek O, Freissmuth M, Singer E, Sitte H (2001) Oligomerization of the Human Serotonin Transporter and of the Rat GABA Transporter 1 Visualized by Fluorescence Resonance Energy Transfer Microscopy in Living Cells J Biol Chem, 276 (6): 3805-3810
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• Sitte HH, Hiptmair B, Zwach J, Pifl C, Singer EA, Scholze P (2001) Quantitative analysis of inward and outward transport rates in cells stably expressing the cloned human serotonin transporter: inconsistencies with the hypothesis of facilitated exchange diffusion Mol Pharmacol, 59: 1129-1137
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2000 Original Articles

• Sitte HH, Scholze P, Schloss P, Pifl C, Singer EA (2000) Characterization of carrier-mediated efflux in human embryonic kidney 293 cells stably expressing the rat serotonin transporter: a superfusion study J Neurochem, 74: 1317-1324
• Scholze P, Zwach J, Kattinger A, Pifl V, Singer EA, Sitte HH (2000) Transporter-mediated release: a superfusion study on human embryonic kidney cells stably expressing the human serotonin transporter J Pharmacol Exp Ther, 293: 870-878p

1999 Original Articles

• Thomet U, Baur R, Scholze P, Sieghart W, Sigel E (1999) Dual mode of stimulation by the beta-carboline ZK91085 of recombinant GABA-A receptor currents: molecular determinants affecting its action Br J Pharmacol, 127: 1231-1239
• Ebert V, Scholze P, Fuchs K, Sieghart W (1999) Identification of subunits mediating clustering of GABA-A receptors by rapsyn Neurochem Internat, 34: 453-463

1996 Original Articles

• Ebert V, Scholze P, Sieghart W (1996) Extensive heterogeneity of recombinant gamma-aminobutyric acid-A receptors expressed in alpha4beta3gamma2-transfected human embryonic kidney 293 cells Neuropharmacology, 35: 1323-1330
• Scholze P, Ebert V, Sieghart W (1996) Affinity of various ligands for GABA-A receptors containing alpha4beta3gamma2, alpha4gamma2, or alpha1beta3gamma2 subunits Eur J Pharmacol, 304: 155-162