Medical NeuroScience Cluster Publications by
Forss-Petter Sonja, Ph.D.:

2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2008 2007 2006 2005 2004 2003 2002 2000 1999 1998 1997

2021 Original Articles

• Rodríguez-Pascau L, Vilalta A, Cerrada M, Traver E, Forss-Petter S, Weinhofer I, Bauer J, Kemp S, Pina G, Pascual S, Meya U, Musolino P, Berger J, Martinell M, Pizcueta P (2021) The brain penetrant PPARγ agonist leriglitazone restores multiple altered pathways in models of X-linked adrenoleukodystrophy Sci Transl Med, 13 (596): eabc0555
• Weinhofer I, Rommer P, Zierfuss B, Altmann P, Foiani M, Heslegrave A, Zetterberg H, Gleiss A, Musolino P, Gong Y, Forss-Petter S, Berger T, Eichler F, Aubourg P, Köhler W, Berger J (2021) Neurofilament light chain as a potential biomarker for monitoring neurodegeneration in X-linked adrenoleukodystrophy Nat Commun, 12 (1)

2020 Original Articles

• Dorninger F, Forss-Petter S, Wimmer I, Berger J (2020) Plasmalogens, platelet-activating factor and beyond – Ether lipids in signaling and neurodegeneration Neurobiol Dis, 145: 105061
• Zierfuss B, Weinhofer I, Kühl J, Köhler W, Bley A, Zauner K, Binder J, Martinović K, Seiser C, Hertzberg C, Kemp S, Egger G, Leitner G, Bauer J, Wiesinger C, Kunze M, Forss-Petter S, Berger J (2020) Vorinostat in the acute neuroinflammatory form of X-linked adrenoleukodystrophy Ann Clin Transl Neurol, 7 (5): 639-652

2019 Original Articles

• Dorninger F, König T, Scholze P, Berger M, Zeitler G, Wiesinger C, Gundacker A, Pollak D, Huck S, Just W, Forss-Petter S, Pifl C, Berger J (2019) Disturbed Neurotransmitter Homeostasis in Ether Lipid Deficiency Hum Mol Genet, 28(12): 2046-2061

2018 Original Articles

• Weinhofer I, Zierfuss B, Hametner S, Wagner M, Popitsch N, Machacek C, Bartolini B, Zlabinger G, Ohradanova-Repic A, Stockinger H, Köhler W, Höftberger R, Regelsberger G, Forss-Petter S, Lassmann H, Berger J (2018) Impaired plasticity of macrophages in X-linked adrenoleukodystrophy Brain, 141: 2329-2342
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• Dorninger F, Moser A, Kou J, Wiesinger C, Forss-Petter S, Gleiss A, Hinterberger M, Jungwirth S, Fischer P, Berger J (2018) Alterations in the Plasma Levels of Specific Choline Phospholipids in Alzheimer’s Disease Mimic Accelerated Aging J. Alzheimers Dis., 62 (2): 841-854
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2017 Original Articles

• Dorninger F, Herbst R, Kravic B, Camurdanoglu B, Macinkovic I, Zeitler G, Forss-Petter S, Strack S, Khan M, Waterham H, Rudolf R, Hashemolhosseini S, Berger J (2017) Reduced Muscle Strength in Ether Lipid-Deficient Mice Is Accompanied by Altered Development and Function of the Neuromuscular Junction J Neurochem, 143: 569-583
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2017 Reviews

• Dorninger F, Forss-Petter S, Berger J (2017) From peroxisomal disorders to common neurodegenerative diseases - the role of ether phospholipids in the nervous system FEBS Letters, 591: 2761-2788
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2016 Reviews

• Berger J, Dorninger F, Forss-Petter S, Kunze M (2016) Peroxisomes in brain development and function Biochim Biophys Acta, 863: 934-955
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2015 Original Articles

• Dorninger F, Wiesinger C, Braverman N, Forss-Petter S, Berger J (2015) Ether Lipid Deficiency Does Not Cause Neutropenia or Leukopenia in Mice and Men Cell Metab, 21 (5): 650-651
• Dorninger F, Brodde A, Braverman N.E, Moser A.B, Just W, Forss-Petter S, Brügger B. Berger J, (2015) Homeostasis of Phospholipids – The Level of Phosphatidylethanolamine Tightly Adapts to Changes in Ethanolamine Plasmalogens Biochim Biophys Acta, 1851: 117-128
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2014 Original Articles

• Muneer Z, Wiesinger C, Voigtländer T, Werner H, Berger J, Forss-Petter S (2014) Abcd2 Is a Strong Modifier of the Metabolic Impairments in Peritoneal Macrophages of Abcd1-Deficient Mice PLoS One, 9 (9): e108655
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• Weber F, Weinhofer I, Einwich A, Forss-Petter S, Muneer Z, Maier H, Weber W, Berger J (2014) Evaluation of Retinoids for Induction of the Redundant Gene ABCD2 as an Alternative Treatment Option in X-Linked Adrenoleukodystrophy PLoS One, 9 (7): e103742
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• Weber F, Wiesinger Ch, Forss-Petter S, Regelsberger G, Einwich A, Weber W, Köhler W, Stockinger H, Berger J, (2014) X-linked adrenoleukodystrophy: Very long-chain fatty acid metabolism is severely impaired in monocytes but not in lymphocytes Hum Mol Genet, 23 (10): 2542-2550
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2014 Reviews

• Berger J, Forss-Petter S, Eichler F.S, (2014) Pathophysiologie of X-linked adrenoleukodystrophy Biochimie, 98: 135-142
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2013 Original Articles

• Pei Z, Fraisl P, Shi X, Gabrielson E, Forss-Petter S, Berger J, Watkins P.A (2013) Very Long-Chain Acyl-COA Synthetase 3:Overexpression and Growth Dependence in Lung Cancer PLoS.ONE., 8(7): e69392
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• Wiesinger C, Kunze M, Regelsberger G, Forss-Petter S, Berger J. (2013) Impaired Very Long-Chain Acyl-CoA β-Oxidation in Human X-ALD Fibroblasts Is a Direct Consequence of ABCD1 Transporter Dysfunction J Biol Chem, 288: 19269-19279

2013 Book Chapters

• Weinhofer I, Kunze M, Forss-Petter S, Berger J (2013) Involvement of Human Peroxisomes in Biosynthesis and Signaling of Steroid and Peptide Hormones. In: del Río, Luis A. (Ed.), Subcellular Biochemistry Vol. 69: Peroxisomes and their Key Role in Cellular Signaling and Metabolism Springer Verlag, Heidelberg: pp 101-110

2012 Original Articles

• Facciotti F, Ramanjaneyulu GS, Lepore M, Sansano S, Cavallari M, Kistowska M, Forss-Petter S, Ni G, Colone A, Singhal A, Berger J, Xia C, Mori L, De Libero G (2012) Peroxisome-derived lipids are self-antigens stimulating invariant Natural Killer T cells in the thymus Nature Immunol, 13(5): 474-480.
• Barbier M, Sabbagh A, Kasper E, Asheuer M, Ahouansou O, Pribill I, Forss-Petter S, Vidaud M, Berger J, Aubourg P (2012) CD1 gene polymorphisms and phenotypic variability in X-linked adrenoleukodystrophy PLoS.ONE., 7(1): e29872
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2011 Original Articles

• Kou J, Kovacs GG, Höftberger R, Kulik W, Brodde A, Forss-Petter S, Hönigschnabl S, Gleiss A, Brügger B, Wanders R, Just W, Budka H, Jungwirth S, Fischer P, Berger J. (2011) Peroxisomal alterations in Alzheimer's disease Acta Neuropathol, 122: 271-283
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2010 Original Articles

• Höftberger R*/Kunze M* (*joint authorship), Voigtländer T, Unterberger U, Regelsberger G, Bauer J, Aboul-Enein F, Garzuly F, Forss-Petter S, Bernheimer H, Berger J, Budka H (2010) Peroxisomal localization of the proopiomelanocortin-derived peptides ß-Lipotropin and ß-Endorphin Endocrinology, 151: 4801-4810
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2010 Reviews

• Berger J, Pujol A, Aubourg P, Forss-Petter S (2010) Current and future pharmacological treatment strategies in X-linked adrenoleukodystrophy. Brain Pathol, 20: 845-856
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2008 Original Articles

• Weinhofer I, Kunze M, Rampler H, Forss-Petter S, Samarut J, Plateroti M, Berger J (2008) Distinct modulatory roles for thyroid hormone receptors TR-alpha and TR-beta in SREBP1-activated ABCD2 expression Eur J Cell Biol, 87: 933-945
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2007 Original Articles

• Dumser M, Bauer J, Lassmann H, Berger J, Forss-Petter S (2007) Lack of adrenoleukodystrophy protein enhances oligodendrocyte disturbance and microglia activation in mice with combined Abcd1/Mag deficiency Acta Neuropathol, 114;6: 573-586

2006 Original Articles

• Fraisl P., Tanaka H., Forss-Petter S, Lassmann H., Nishimune Y., Berger J (2006) A novel mammalian bubblegum-related acyl-CoA synthetase restricted to testes and possibly involved in spermatogenesis Arch Biochem Biophys, 451: 23-33

2005 Original Articles

• Oezen I., Rossmanith W., Forss-Petter S., Kemp S., Voigtländer T., Moser-Thier., Wanders R., Bittner R., Berger J (2005) Accumulation of very long-chain fatty acids does not affect mitochondrial function in Adrneoleukodystrophy protein deficiency Hum Mol Genet, 14: 1127-1137
• Weinhofer I., Kunze M., Rampler H., Bookout A.L., Forss-Petter S., Berger J (2005) LXRalpha interferes with SREBP1c-mediated Abcd2 expression: novel cross-talk in gene regulation J Biol Chem, 280: 41243-41251

2004 Original Articles

• Fraisl P., Forss-Petter S., Zigman M., Berger J. (2004) Murine bubblegum orthologue is a microsomal very long-chain acyl-CoA synthetase Biochemistry, 377: 85-93
• Pei Z., Fraisl P., Berger J., Jia Z., Forss-Petter S., Watkins P (2004) Mouse very long-chain acyl-CoA synthetase 3/Fatty Acid Transporter Protein 3 Catalyzes fatty acid activation but not fatty acid transport in MA-10 cells J Biol Chem, 279: 54454-54462

2003 Original Articles

• Weinhofer I, Forss-Petter S, Zigman M, Berger J (2003) Cholesterol regulates ABCD2 gene expression: implications for X-linked adrenoleukodstrophy Adv Exp Med Biol, 544: 331-332
• Rampler H., Weinhofer I., Netik A., Forss-Petter S., Brown PJ., Oplinger JA., Bugaut M., Berger J (2003) Evaluation of the therapeutic potential of PPAR alpha agonists for X-linked adrenoleukodystrophy. Mol Genet Metab, 80: 398-407

2002 Original Articles

• Weinhofer I., Forss-Petter S., Zigman M., Berger J (2002) Cholesterol regulates ABCD2 expression: Implication for therapy of X-linked adrenoleukodystrophy Hum Mol Genet, 11: 2701-2708

2000 Original Articles

• Nöhammer C., El Shabrawi Y., Schauer S., Hiden M., Berger J., Forss-Petter S., Winter E., Eferl R., Zechner R., Höfler G. (2000) cDNA cloning and analysis of issue-specific expression of mouse peroxisomal acyl-CoA oxidase Eur J Biochem, 267: 1254-1260
• Unterrainer G., Molzer B., Forss-Petter S., Berger J (2000) Coexpression of mutated adrenoleukodystrophy protein reduces wild-type protein function: Implication for gene therapy in X-linked adrenoleukodystrophy Hum Mol Genet, 9: 2609-2616
• Netik A., Hobel A., Rauschka H., Molzer B., Forss-Petter S., Berger J (2000) Rolipram does not normalize very long chain fatty acid levels in adrenoleukodystrophy protein-deficient fibroblasts and mice J Inhereted Metab Dis, 23: 615-624

1999 Original Articles

• Berger J., Albet S., Bentejac M., Netik A., Holzinger A., Roscher A., Bugaut M., Forss-Petter S (1999) The four murine peroxisomal ABC-transporter genes differ in constitutive, inducible and developmental expression Eur J Biochem, 265: 719-727

1998 Original Articles

• Berger J., Truppe C., Neumann H., Forss-Petter S (1998) A novel relative of the very long-chain acyl-CoA synthetase and fatty acid transporter protein genes with a distinct expression pattern Biochem Bioph Res Comm, 247: 255-260
• Berger J., Truppe C., Neumann H., Forss-Petter S. (1998) cDNA cloning and mRNA distribution of a mouse very long-chain acyl-CoA synthetase FEBS Letters, 425: 305-309
• Bauer, J., Bradl, M., Hickey, W.F., Forss-Petter, S., Breitschopf, H., Linington, C., Wekerle, H., and Lassmann, H (1998) T cell apoptosis in inflammatory brain lesions. Destruction of T cells does not depend on antigen recognition Am.J.Pathol., 153: 715-724

1997 Original Articles

• Forss-Petter S, Werner H, Berger J, Lassmann H, Molzer B, Schwab MH, Bernheimer H, Zimmermann F, Nave KA (1997) Targeted inactivation of the X-linked adrenoleucodystrophy gene in mice. J Neurosci Res, 50: 829-843

1997 Reviews

• Berger J., Bernheimer H., Forss-Petter S (1997) False PCR-based diagnosis: is it avoidable? Am J Med Genet, 72: 241