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Inhaltsbereich

Assoc.Prof.Priv.Doz.Dr. Ornella Valenti, MSc

Department(s): Department of Neurophysiology and Neuropharmacology (Center for Physiology and Pharmacology)
Position: Associate Professor
Location: Schwarzspanierstraße 17
Telephone: 40160-31220
E-Mail:

Research Area:
Biological Psychiatry, Neuropharmacology, Neurophysiology and behavioral


Research Interests:
Adenosine, Affective Disorders, Psychotic, Alzheimer Disease, Association Learning, Cerebral Cortex, Cognition Disorders, Decision Making, Dopamine, Electrophysiology, Extinction, Psychological, GABAergic Neurons, Limbic System, Memory, Mental Retardation, X-Linked, Motivation, Receptors, Metabotropic Glutamate, Reward, Schizophrenia, Stress, Physiological


Principle Investigator(s):

  • Valenti, Ornella (Head)
  • Valenti, Ornella


Interest Group(s):

  • AddRess - Center for Addiction Research & Science
  • Neurobiology of Emotion and Cognition
  • Neuropsychopharmacology


Abstract:

I am interested in neuronal circuits supporting cognition, motivation, and pro-social behavior.  In addition, I examine the means by which the experience of early-life stress might enhance the risk of developing psychiatric disorders, including schizophrenia. 


Techniques:

We employ a system as well as a cellular approach in behavioral and genetic murine models, and investigate the dynamics of specific neuronal circuits by a battery of electrophysiological approaches and pharmacological manipulations. As part of Prof. Boehm group, we also have access to confocal and fluorescence microscopes, and to a molecular biology lab. Techniques include:

  • Electrophysiology, in-vivo and ex-vivo single unit recordings from anesthetized rodents;
  • Electrophysiology, whole-cell patch-clamp recordings from rodent acute slices;
  • Pharmacological and chemogenetic manipulation of brain circuits;
  • Cognitive and motivational behavioral tasks;
  • Rodent models of psychosis, motivation and stress disorders;
  • Immunohistochemistry

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